{"id":9096,"date":"2020-05-07T14:11:40","date_gmt":"2020-05-07T12:11:40","guid":{"rendered":"https:\/\/staging.ggba.swiss\/le-clone-bernois-du-coronavirus-devient-viral\/"},"modified":"2023-07-04T13:43:22","modified_gmt":"2023-07-04T11:43:22","slug":"le-clone-bernois-du-coronavirus-devient-viral","status":"publish","type":"post","link":"https:\/\/staging.ggba.swiss\/fr\/le-clone-bernois-du-coronavirus-devient-viral\/","title":{"rendered":"Le clone bernois du coronavirus devient \u00ab\u00a0viral\u00a0\u00bb"},"content":{"rendered":"

Mi-f\u00e9vrier, une \u00e9quipe de chercheurs de l’universit\u00e9 de Berne est parvenue \u00e0 reconstruire un clone synth\u00e9tique du coronavirus gr\u00e2ce \u00e0 un nouveau syst\u00e8me qui utilise des cellules de levure. Des scientifiques du monde entier utilisent \u00e0 pr\u00e9sent ces clones synth\u00e9tiques pour tester des \u00e9chantillons et d\u00e9velopper des vaccins le plus rapidement possible.<\/h4>\n

Alors que le nombre d\u2019infections confirm\u00e9es au coronavirus d\u00e9passe les 3,7 millions dans le monde, les chercheurs et les entreprises pharmaceutiques du monde entier travaillent d\u2019arrache-pied pour tester plus efficacement des \u00e9chantillons et d\u00e9velopper des vaccins. Pour ce faire, nombre d’entre eux utilisent les copies synth\u00e9tiques du virus qui ont \u00e9t\u00e9 d\u00e9velopp\u00e9es en Suisse, au sein du laboratoire de haute s\u00e9curit\u00e9 de l\u2019Institut de virologie et d\u2019immunologie (IVI<\/a>) de l\u2019Office f\u00e9d\u00e9ral de la s\u00e9curit\u00e9 alimentaire et des affaires v\u00e9t\u00e9rinaires (OSAV<\/a>) \u00e0 Mittelh\u00e4usern et \u00e0 la facult\u00e9 Vetsuisse<\/a> de l\u2019Universit\u00e9 de Berne<\/a>.<\/p>\n

Plus petits que les plus petites bact\u00e9ries et extr\u00eamement mutables, les virus sont tr\u00e8s difficiles \u00e0 cloner. Gr\u00e2ce \u00e0 une nouvelle m\u00e9thode qui utilise des cellules de levure, les scientifiques suisses sont parvenus \u00e0 reconstruire le nouveau coronavirus en une semaine. Les r\u00e9sultats de leur \u00e9tude ont \u00e9t\u00e9 publi\u00e9s dans le journal Nature<\/a>.<\/em><\/p>\n

Le mod\u00e8le bernois<\/h4>\n

Pour cloner le coronavirus, des morceaux de son g\u00e9nome ont \u00e9t\u00e9 produits \u00e0 partir d\u2019ADN synth\u00e9tique et r\u00e9assembl\u00e9s dans des cellules de levure \u00e0 l\u2019aide d\u2019un processus connu sous le nom de recombinaison associ\u00e9e \u00e0 la transformation. Il en a r\u00e9sult\u00e9 un chromosome artificiel de levure qui contenait les informations g\u00e9n\u00e9tiques du virus. De l\u2019ARN infectieux a ensuite \u00e9t\u00e9 cr\u00e9\u00e9 in vitro, puis int\u00e9gr\u00e9 dans des cellules animales, o\u00f9 les nouveaux coronavirus synth\u00e9tiques se sont multipli\u00e9s. Cette m\u00e9thode permet de r\u00e9agir rapidement \u00e0 l\u2019\u00e9mergence de nouveaux virus \u00e0 propagation rapide.<\/p>\n","protected":false},"excerpt":{"rendered":"

Mi-f\u00e9vrier, une \u00e9quipe de chercheurs de l’universit\u00e9 de Berne est parvenue \u00e0 reconstruire un clone synth\u00e9tique du coronavirus gr\u00e2ce \u00e0 un nouveau syst\u00e8me qui utilise des cellules de levure. Des scientifiques du monde entier utilisent \u00e0 pr\u00e9sent ces clones synth\u00e9tiques pour tester des \u00e9chantillons et d\u00e9velopper des vaccins le plus rapidement possible. Alors que le […]<\/p>\n","protected":false},"author":3,"featured_media":9097,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"mc4wp_mailchimp_campaign":[]},"categories":[843,842],"tags":[1027,1069],"acf":[],"yoast_head":"\nLe clone bernois du coronavirus devient \u00ab\u00a0viral\u00a0\u00bb - Greater Geneva Bern area<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Le clone bernois du coronavirus devient \u00ab\u00a0viral\u00a0\u00bb - Greater Geneva Bern area\" \/>\n<meta property=\"og:description\" content=\"Mi-f\u00e9vrier, une \u00e9quipe de chercheurs de l’universit\u00e9 de Berne est parvenue \u00e0 reconstruire un clone synth\u00e9tique du coronavirus gr\u00e2ce \u00e0 un nouveau syst\u00e8me qui utilise des cellules de levure. Des scientifiques du monde entier utilisent \u00e0 pr\u00e9sent ces clones synth\u00e9tiques pour tester des \u00e9chantillons et d\u00e9velopper des vaccins le plus rapidement possible. 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