{"id":7949,"date":"2016-03-18T12:51:00","date_gmt":"2016-03-18T11:51:00","guid":{"rendered":"https:\/\/staging.ggba.swiss\/un-implant-pour-lutter-contre-la-maladie-dalzheimer\/"},"modified":"2023-07-04T13:42:58","modified_gmt":"2023-07-04T11:42:58","slug":"un-implant-pour-lutter-contre-la-maladie-dalzheimer","status":"publish","type":"post","link":"https:\/\/staging.ggba.swiss\/fr\/un-implant-pour-lutter-contre-la-maladie-dalzheimer\/","title":{"rendered":"Un implant pour lutter contre la maladie d’Alzheimer"},"content":{"rendered":"

Des scientifiques de l’EPFL ont d\u00e9velopp\u00e9 un implant sous-cutan\u00e9 qui pourrait permettre de traiter la maladie d’Alzheimer.<\/b><\/p>\n

L’une des causes pr\u00e9sum\u00e9es de la maladie d’Alzheimer est l’accumulation de la prot\u00e9ine b\u00eata-amylo\u00efde (Abeta) dans diff\u00e9rentes zones du cerveau. Un moyen prometteur visant \u00e0 neutraliser ces d\u00e9p\u00f4ts anormaux de prot\u00e9ines, qui sont toxiques pour les neurones, consiste \u00e0 les \u00ab marquer \u00bb avec des anticorps qui alertent le propre syst\u00e8me immunitaire du patient, afin qu\u2019il les attaque et les \u00e9limine. Afin d’\u00e9viter les effets secondaires provoqu\u00e9s par des injections r\u00e9p\u00e9t\u00e9es de vaccin, le laboratoire de Patrick Aebischer<\/link> \u00e0 l\u2019EPFL<\/link> a mis au point un implant qui d\u00e9livre un flux d’anticorps r\u00e9gulier et inoffensif dans le cerveau du patient afin d’\u00e9liminer les prot\u00e9ines Abeta. <\/p>\n

Les chercheurs ont test\u00e9 le dispositif sur des souris sur une p\u00e9riode de 10 mois avec un \u00ab succ\u00e8s complet \u00bb, indique un communiqu\u00e9<\/link>. Les souris \u2013 une lign\u00e9e g\u00e9n\u00e9tique couramment utilis\u00e9e pour simuler la maladie d\u2019Alzheimer \u2013 ont pr\u00e9sent\u00e9 une diminution spectaculaire de la charge en plaques. D\u00e9crit comme un \u00ab dispositif de macro-encapsulation \u00bb, le dispositif peut \u00eatre facilement reproduit pour une production \u00e0 grande \u00e9chelle.<\/p>\n

Ce travail, publi\u00e9 dans la revue Brain, d\u00e9montre clairement que des implants cellulaires encapsul\u00e9s peuvent \u00eatre utilis\u00e9s avec succ\u00e8s et sans risques pour d\u00e9livrer des anticorps afin de traiter la Maladie d\u2019Alzheimer et d\u2019autres d\u00e9sordres neurod\u00e9g\u00e9n\u00e9ratifs impliquant des prot\u00e9ines d\u00e9fectueuses.<\/p>\n","protected":false},"excerpt":{"rendered":"

Des scientifiques de l’EPFL ont d\u00e9velopp\u00e9 un implant sous-cutan\u00e9 qui pourrait permettre de traiter la maladie d’Alzheimer. L’une des causes pr\u00e9sum\u00e9es de la maladie d’Alzheimer est l’accumulation de la prot\u00e9ine b\u00eata-amylo\u00efde (Abeta) dans diff\u00e9rentes zones du cerveau. Un moyen prometteur visant \u00e0 neutraliser ces d\u00e9p\u00f4ts anormaux de prot\u00e9ines, qui sont toxiques pour les neurones, consiste […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"mc4wp_mailchimp_campaign":[]},"categories":[842],"tags":[],"acf":[],"yoast_head":"\nUn implant pour lutter contre la maladie d'Alzheimer - Greater Geneva Bern area<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Un implant pour lutter contre la maladie d'Alzheimer - Greater Geneva Bern area\" \/>\n<meta property=\"og:description\" content=\"Des scientifiques de l’EPFL ont d\u00e9velopp\u00e9 un implant sous-cutan\u00e9 qui pourrait permettre de traiter la maladie d’Alzheimer. L’une des causes pr\u00e9sum\u00e9es de la maladie d’Alzheimer est l’accumulation de la prot\u00e9ine b\u00eata-amylo\u00efde (Abeta) dans diff\u00e9rentes zones du cerveau. 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